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Peptide Directory

Category · 16 peptides

Hormone & Reproductive

Peptides studied for the HPG axis, fertility, and endocrine signaling.

B7-33Preclinical
A single-chain 26-amino-acid relaxin analog engineered as a biased RXFP1 agonist to deliver the anti-fibrotic and cardioprotective effects of H2 relaxin in a simpler synthetic form.
  • Anti-fibrotic activity
  • Cardiovascular protection
  • Renal protection
2 studiesdosing4 stacks
CetrorelixFDA-Approved
An FDA-approved synthetic GnRH antagonist that rapidly suppresses LH and FSH to prevent premature ovulation during IVF cycles.
  • Prevents premature LH surges
  • No initial hormonal flare
  • HPG axis suppression
5 studiesdosing
DesmopressinFDA-Approved
An FDA-approved synthetic vasopressin analogue that raises water reabsorption and clotting factor release while sparing blood-pressure effects.
  • Antidiuretic (water reabsorption)
  • Hemostasis support
  • Reduced nocturia in older adults
8 studiesdosing
EPO (Erythropoietin)FDA-Approved
A kidney-derived glycoprotein hormone that drives red blood cell production and is FDA-approved for treating anemia.
  • Corrects anemia
  • Stimulates erythropoiesis
  • Tissue-protective signaling
FSHFDA-Approved
The pituitary glycoprotein hormone that drives gametogenesis in both sexes and forms the backbone of assisted-reproduction ovarian stimulation.
  • Ovarian stimulation for assisted reproduction
  • Follicular development and estradiol synthesis
  • Spermatogenesis support
10 studies
GonadorelinEstablished
Synthetic gonadotropin-releasing hormone that sits at the very top of the reproductive axis, driving pulsatile pituitary LH and FSH release.
  • Pulsatile LH and FSH stimulation
  • Testicular function maintenance during TRT
  • Fertility preservation via intact FSH pathway
3 studiesdosing4 stacks
hCGEstablished
A long-acting LH mimetic that directly stimulates the testes to make testosterone and preserve fertility, and triggers ovulation in fertility medicine.
  • Direct testicular testosterone stimulation
  • Testicular size and function preservation on TRT
  • Fertility restoration and spermatogenesis support
8 studiesdosing4 stacks
Kisspeptin-10Emerging
The master upstream trigger of the reproductive axis — a hypothalamic neuropeptide that ignites GnRH release and the entire LH/FSH/testosterone cascade.
  • Activates the entire HPG axis from the top
  • Testosterone and spermatogenesis support
  • Ovulation triggering with lower OHSS risk
9 studiesdosing3 stacks
LeuprolideFDA-Approved
A synthetic GnRH superagonist that paradoxically shuts down sex-hormone production by desensitizing the pituitary, producing medical castration levels of testosterone and estrogen.
  • Androgen deprivation for prostate cancer
  • Estrogen suppression for endometriosis and fibroids
  • Treatment of central precocious puberty
9 studiesdosing1 stacks
LHModerate
The pituitary gonadotropin that drives testosterone synthesis in men and triggers ovulation in women.
  • Testosterone stimulation
  • Ovulation induction
  • Fertility support
9 studiesdosing1 stacks
OxytocinFDA-Approved
The endogenous 'love hormone' — a nine-amino-acid neuropeptide, FDA-approved as Pitocin for labor since 1962 and widely researched off-label for social bonding, anxiety, and sexual connection.
  • Labor induction and postpartum hemorrhage control
  • Prosocial behavior and trust
  • Social attention and emotional processing
9 studiesdosing2 stacks
RelaxinEmerging
An insulin-family peptide hormone that acts through the RXFP1 receptor to drive vasodilation, boost renal perfusion, and suppress fibrotic tissue remodeling.
  • Systemic vasodilation
  • Anti-fibrotic remodeling
  • Increased renal perfusion
8 studiesdosing
TeriparatideFDA-Approved
A synthetic parathyroid hormone fragment and the first FDA-approved anabolic agent that builds new bone rather than merely slowing its loss.
  • Stimulates new bone formation
  • Increases bone mineral density
  • Reduces fracture risk
6 studiesdosing1 stacks
TRHEmerging
A hypothalamic tripeptide that drives TSH release from the pituitary while acting as a broad CNS neuromodulator with arousal-promoting and neuroprotective effects.
  • Cognitive enhancement
  • Neuroprotection
  • Arousal and wakefulness
2 studiesdosing
TriptorelinFDA-Approved
A long-acting synthetic GnRH agonist that is FDA-approved for hormonal suppression, but whose brief initial LH/FSH flare drives its off-label reputation as a single-shot HPG-axis restart.
  • Androgen deprivation for prostate cancer
  • Central precocious puberty control
  • Endometriosis and uterine fibroid management
6 studiesdosing2 stacks
VasopressinFDA-Approved
An endogenous hypothalamic nonapeptide hormone that regulates water balance, blood pressure, and stress-related memory, and is FDA-approved as a vasopressor for shock.
  • Vasopressor support in shock
  • Water balance and antidiuresis
  • Memory consolidation
7 studiesdosing
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