Peptide Directory
152 peptides, organized by what they do
In-depth profiles covering mechanisms, researched benefits, dosing protocols, clinical studies, and stacking — grouped into nine benefit-based categories so you can navigate by goal.
152 profiles9 categories585+ cited studies
Browse by benefit
Healing & Recovery
20Peptides studied for tissue repair, wound healing, tendon/ligament recovery, and gut protection.
ExploreWeight Loss & Metabolic
20GLP-1 and metabolic peptides studied for fat loss, appetite regulation, and glucose control.
ExploreGrowth Hormone & Performance
23GHRH, GHRP/ghrelin secretagogues, and IGF peptides studied for GH release, recovery, and body composition.
ExploreCognitive & Nootropic
21Peptides studied for focus, memory, mood, neuroprotection, and sleep.
ExploreLongevity & Bioregulators
24Khavinson bioregulator peptides and senotherapeutics studied for cellular aging and organ-specific regulation.
ExploreSkin, Hair & Cosmetic
11Peptides studied for collagen synthesis, skin remodeling, wrinkle reduction, and hair growth.
ExploreSexual Health & Melanocortin
4Melanocortin and reproductive-axis peptides studied for libido, arousal, and tanning.
ExploreHormone & Reproductive
16Peptides studied for the HPG axis, fertility, and endocrine signaling.
ExploreImmune & Mitochondrial
13Peptides studied for immune modulation, mitochondrial function, and cellular energy.
Explore20 peptides
Healing & Recovery
Peptides studied for tissue repair, wound healing, tendon/ligament recovery, and gut protection.
Ac-SDKPPreclinical
An endogenous anti-fibrotic tetrapeptide derived from thymosin beta-4 that curbs collagen deposition and inflammation in preclinical tissue-repair models.6 benefits4 studiesAngiotensin 1-7Emerging
An endogenous heptapeptide that forms the protective, counter-regulatory arm of the renin-angiotensin system by activating the Mas receptor.7 benefits10 studiesdosingARA-290Emerging
A non-hematopoietic erythropoietin fragment engineered to trigger tissue repair and quiet inflammation without raising red blood cells.5 benefits3 studiesdosingBPC-157Preclinical
A stable gastric pentadecapeptide with an extraordinary preclinical record for tissue repair across tendon, gut, nerve, and vascular tissue — and almost no controlled human trials.6 benefits9 studiesdosingBPC-157 + KPV BlendPreclinical
A gut-and-repair pairing that combines BPC-157's tissue-rebuilding signal with KPV's NF-kB anti-inflammatory action.6 benefits1 studiesdosingBPC-157 + TB-500 BlendPreclinical
The "wolverine stack" that pairs BPC-157 and TB-500 in one vial for complementary tissue-repair pathways, backed by strong component preclinical data but zero controlled trials on the blend itself.5 benefits3 studiesdosingDalarginPreclinical
A Soviet-developed synthetic enkephalin analog studied mainly for gastroprotective and anti-ulcer activity through peripheral opioid receptors.5 benefits1 studiesEGFEmerging
An endogenous 53-amino-acid growth factor that binds EGFR to drive skin regeneration, wound re-epithelialization, and collagen production.5 benefits6 studiesdosingFGF-1Emerging
An endogenous heparin-binding growth factor that binds all four FGF receptors to drive angiogenesis, wound healing, and tissue repair.5 benefits2 studiesGHK-Cu + BPC-157 BlendEmerging
A single-vial pairing of GHK-Cu and BPC-157 that combines skin and collagen repair with connective-tissue and gut healing.5 benefits2 studiesdosingGLOW BlendPreclinical
A cosmetic-first three-peptide blend of GHK-Cu, BPC-157, and TB-500, weighted heavily toward GHK-Cu for skin, hair, and post-procedure recovery.5 benefitsdosingGLP-2Established
An intestinal growth hormone that repairs and reinforces the gut lining, validated clinically through its stabilized analog teduglutide.5 benefits6 studiesKGF-1FDA-Approved
An epithelium-specific fibroblast growth factor that signals through FGFR2b to protect and regenerate keratinocytes and mucosal surfaces.5 benefits1 studiesKLOW BlendPreclinical
A compounded four-peptide clinic blend (KPV + GHK-Cu + BPC-157 + TB-500) built for skin, hair, collagen, and tissue recovery in a single injection.6 benefitsdosingKPVPreclinical
A three-amino-acid fragment of alpha-MSH that delivers targeted NF-κB anti-inflammatory action without the parent hormone's tanning, appetite, or arousal effects.6 benefits4 studiesdosingLarazotideEmerging
A synthetic octapeptide zonulin antagonist that tightens the intestinal barrier by preventing zonulin-mediated disassembly of epithelial tight junctions.4 benefits3 studiesdosingLL-37Emerging
The only human cathelicidin antimicrobial peptide — a broad-spectrum, membrane-disrupting innate-immune peptide with antibacterial, antiviral, antifungal, and wound-healing activity.6 benefits11 studiesdosingPDRNEstablished
A salmon-DNA-derived polynucleotide that accelerates wound healing and skin rejuvenation through adenosine A2A receptor activation.6 benefitsdosingTB-500Emerging
A synthetic fragment of thymosin beta-4 studied for tissue repair, cell migration, and systemic recovery — most famous as BPC-157's partner in the "Wolverine stack."7 benefits8 studiesdosingTeduglutideFDA-Approved
An FDA-approved GLP-2 receptor agonist that regrows intestinal mucosa to restore absorptive capacity in short bowel syndrome.5 benefits7 studiesdosing20 peptides
Weight Loss & Metabolic
GLP-1 and metabolic peptides studied for fat loss, appetite regulation, and glucose control.
5-Amino-1MQPreclinical
An orally active small-molecule NNMT inhibitor with reproducible fat-loss and muscle data in mice but zero published human trials.5 benefits7 studiesdosingAdipotidePreclinical
A synthetic peptidomimetic that starves white fat tissue by triggering apoptosis in the blood vessels that feed it.4 benefits3 studiesAICARPreclinical
A non-peptide AMPK-activating nucleotide analog studied as an "exercise mimetic" for endurance, fat oxidation, and metabolic regulation.5 benefits8 studiesAOD-9604Emerging
A tyrosine-modified fragment of growth hormone engineered to isolate GH's fat-burning action from its growth effects, that cleanly delivered selective lipolysis in trials but failed to produce meaningful weight loss in humans.5 benefits3 studiesdosingCagrilintideModerate
A long-acting amylin analogue that reinforces satiety through a pathway distinct from GLP-1, best known as the amylin half of the CagriSema combination.6 benefits10 studiesdosingCagriSemaEstablished
The first fixed-dose GLP-1 plus amylin combination, pairing semaglutide and cagrilintide in a single once-weekly injection for deep weight loss.5 benefits3 studiesdosingExenatideEmerging
A GLP-1 receptor agonist researched for its effects on metabolism and appetite regulation.2 benefitsGLP-1 (7-37)Emerging
The native, full-length active form of glucagon-like peptide-1 — the endogenous incretin hormone that the entire GLP-1 receptor agonist drug class is modeled on.6 benefits2 studiesdosingHGH Fragment 176-191Preclinical
The C-terminal fat-burning fragment of growth hormone, designed to isolate lipolysis without the IGF-1 and growth effects of full GH — but whose clinical-development cousin AOD-9604 failed its pivotal obesity trial.5 benefits4 studiesdosingLiraglutideFDA-Approved
The first long-acting GLP-1 receptor agonist approved for obesity, a once-daily injection that reduces appetite and blood sugar.6 benefits12 studiesdosingMazdutideEstablished
A once-weekly dual GLP-1/glucagon receptor agonist that became the first dual incretin approved for obesity, reaching market in China in 2025.5 benefits4 studiesdosingOrforglipronFDA-Approved
The first non-peptide, small-molecule oral GLP-1 receptor agonist — a once-daily weight-management pill, no injection required.5 benefits7 studiesdosingOxyntomodulinModerate
An endogenous gut hormone that acts as a dual GLP-1/glucagon receptor agonist, suppressing appetite while raising energy expenditure.5 benefits5 studiesdosingPramlintideFDA-Approved
An FDA-approved synthetic amylin analogue that slows gastric emptying, suppresses glucagon, and enhances meal-related satiety.5 benefits4 studiesdosingRetatrutideEmerging
An investigational once-weekly triple GLP-1/GIP/glucagon receptor agonist that has produced the deepest weight-loss numbers ever recorded in obesity trials.6 benefits10 studiesdosingSemaglutideFDA-Approved
The FDA-approved GLP-1 receptor agonist that turned obesity into a pharmacology problem, delivering ~15% body weight loss with once-weekly dosing.6 benefits8 studiesdosingSLU-PP-332Preclinical
A small-molecule pan-ERR agonist marketed as 'exercise in a pill' with reproducible endurance and fat-oxidation data in mice and zero human evidence.6 benefits4 studiesdosingSLU-PP-915Preclinical
The orally active successor to SLU-PP-332: the same pan-ERR exercise-mimetic mechanism, chemically re-engineered to survive the gut, but still mouse-only.5 benefits2 studiesSurvodutideModerate
An investigational once-weekly dual GLP-1/glucagon receptor agonist delivering strong weight loss plus a standout liver-fat (MASH) effect.5 benefits3 studiesdosingTirzepatideFDA-Approved
A once-weekly dual GIP/GLP-1 receptor agonist that produced the largest mean weight loss of any FDA-approved anti-obesity medication and beat semaglutide head-to-head.6 benefits8 studiesdosing23 peptides
Growth Hormone & Performance
GHRH, GHRP/ghrelin secretagogues, and IGF peptides studied for GH release, recovery, and body composition.
ACE-031Emerging
A soluble decoy receptor fusion protein that sequesters myostatin and related muscle-suppressing ligands to release multiple brakes on muscle and bone growth at once.4 benefits1 studiesCJC-1295 (no DAC)Emerging
A short-acting, DPP-4-resistant GHRH analog that drives sharp, physiologic pulses of the body's own growth hormone.6 benefits4 studiesdosingCJC-1295 + Ipamorelin BlendEmerging
The clinic-standard GH-axis pairing that combines a GHRH analog and a selective GHRP in one vial to amplify the body's own growth hormone pulses through two separate receptors.6 benefits1 studiesdosingCJC-1295 DACEmerging
A long-acting GHRH analog whose Drug Affinity Complex binds albumin to stretch its half-life to roughly a week, producing sustained GH and IGF-1 elevation from a single weekly injection.5 benefits1 studiesdosingFollistatin 344Preclinical
A 344-amino-acid recombinant follistatin isoform that sequesters myostatin and activin A to release the natural brake on skeletal muscle growth.5 benefits2 studiesdosingGhrelinEmerging
The body's endogenous 'hunger hormone' and natural ligand for the growth hormone secretagogue receptor, driving both GH release and appetite.4 benefits9 studiesGHRP-2Moderate
A first-generation synthetic hexapeptide ghrelin-receptor agonist that drives potent pulsatile growth hormone release, at the cost of modest cortisol, prolactin, and appetite stimulation.6 benefits2 studiesdosingGHRP-6Emerging
The original ghrelin-receptor GH secretagogue, distinguished by the strongest appetite stimulation of the GHRP class.5 benefits2 studiesdosingHexarelinEmerging
The most potent growth hormone secretagogue in the GHRP class, with a unique CD36-mediated cardioprotective mechanism separate from its GH-releasing activity.5 benefits2 studiesdosingHGH (Somatropin)FDA-Approved
The original recombinant anabolic peptide drug: a 191-amino-acid copy of human growth hormone, FDA-approved for decades in true deficiency and heavily criminalized off-label.6 benefits3 studiesdosingIGF-1Emerging
The liver-derived 70-amino-acid polypeptide that serves as the principal mediator of growth hormone's anabolic effects on muscle, bone, and tissue.5 benefits8 studiesIGF-1 DESPreclinical
A truncated IGF-1 variant missing its first three amino acids, trading systemic reach for potent, short-lived anabolic action at the injection site.5 benefitsdosingIGF-1 LR3Preclinical
A long-acting synthetic IGF-1 analog engineered to escape binding-protein control and drive sustained, supraphysiologic IGF-1 receptor signaling for muscle growth.5 benefits2 studiesdosingIGF-2Emerging
An endogenous embryonic growth factor and IGF-1 relative that acts as an autocrine driver of muscle cell differentiation through the IGF-1 receptor.5 benefits7 studiesIpamorelinEmerging
The cleanest of the growth hormone-releasing peptides: a selective ghrelin-receptor agonist that triggers a natural GH pulse without spiking cortisol, prolactin, or ACTH.6 benefits4 studiesdosingMGFPreclinical
A locally acting IGF-1 splice variant that switches muscle satellite cells out of quiescence to drive the earliest phase of muscle repair after mechanical loading.6 benefits2 studiesdosingMK-677 (Ibutamoren)Moderate
An orally active, non-peptide ghrelin receptor agonist that drives sustained growth hormone and IGF-1 elevation from a single daily dose.6 benefits4 studiesdosingMyostatin PropeptidePreclinical
The endogenous N-terminal prodomain of myostatin (GDF-8) that neutralizes mature myostatin to release the brakes on skeletal muscle growth.4 benefits2 studiesPEG-MGFPreclinical
A PEGylated version of Mechano Growth Factor engineered to extend the muscle-satellite-cell-activating action of the IGF-1 splice variant from minutes to days.5 benefitsdosingSermorelinEstablished
The original FDA-approved GHRH analog that stimulates the pituitary to release growth hormone in a natural, pulsatile pattern.6 benefits3 studiesdosingSermorelin + GHRP BlendModerate
The legacy GH-axis pairing that predates the clean ipamorelin stacks, combining a GHRH analog with a non-selective ghrelin-receptor agonist to amplify the growth hormone pulse.4 benefits6 studiesdosingTesamorelinFDA-Approved
The only FDA-approved GHRH analog, engineered to stimulate the body's own pulsatile growth hormone release and selectively strip away deep visceral abdominal fat.6 benefits6 studiesdosingTesamorelin + Ipamorelin BlendModerate
A GH-axis pairing built on tesamorelin, the only GHRH analog with a full FDA approval, run alongside the cleanly selective GHRP ipamorelin.5 benefits3 studiesdosing21 peptides
Cognitive & Nootropic
Peptides studied for focus, memory, mood, neuroprotection, and sleep.
9-Me-BCPreclinical
A synthetic β-carboline alkaloid studied preclinically for promoting dopaminergic neuron growth and boosting dopamine synthesis.5 benefitsdosingAdalankPreclinical
A vendor-formulated hybrid research peptide fusing Adamax-style cognitive enhancement with Selank-style anxiolysis in a single molecule.7 benefitsdosingAdamaxPreclinical
A designer Semax analog engineered for deeper brain penetration and a dramatically longer receptor-binding window than its parent nootropic.6 benefits2 studiesdosingBromantaneEmerging
A Russian adamantane-derived actoprotector that gently raises endogenous dopamine synthesis to deliver crash-free stimulation with an unusual anxiolytic, rather than anxiogenic, profile.6 benefits1 studiesdosingCerebrolysinEmerging
A porcine brain-derived neuropeptide complex that mimics endogenous neurotrophic factors to support neuronal survival, plasticity, and recovery after brain injury.6 benefits5 studiesdosingCerlutenEmerging
A Khavinson-class ultrashort peptide bioregulator proposed to protect neural tissue and support cognition through gene-expression regulation.4 benefits2 studiesCortexinEmerging
A porcine/bovine cortex-derived polypeptide bioregulator used clinically in Russia as a neuroprotective and nootropic agent.6 benefits2 studiesdosingDavunetideEmerging
A synthetic ADNP-derived octapeptide investigated as a microtubule-stabilizing neuroprotectant for schizophrenia and tauopathies.5 benefits3 studiesdosingDihexaPreclinical
A synthetic angiotensin IV-derived compound that potentiates HGF/c-Met signaling to drive synaptogenesis, with striking rodent potency but zero human trials.5 benefits2 studiesdosingDSIPPreclinical
A naturally occurring nine-amino-acid neuropeptide named for its association with delta-wave sleep, researched for decades for sleep architecture, stress modulation, and withdrawal support.6 benefits1 studiesdosingFGLPreclinical
A synthetic 15-amino-acid NCAM-derived peptide that mimics neural cell adhesion molecule signaling to promote synaptic plasticity and neuroprotection in preclinical models.5 benefitsHLDF-6Preclinical
A synthetic hexapeptide (TGENHR) derived from the HLDF protein, investigated preclinically for neuroprotection in Alzheimer's and Parkinson's models.5 benefitsN-Acetyl SelankPreclinical
An acetylated derivative of the anxiolytic heptapeptide Selank, engineered for greater enzymatic stability and CNS bioavailability.5 benefitsN-Acetyl SemaxPreclinical
An acetylated (and often amidated) analog of the Russian nootropic Semax, engineered to resist enzymatic breakdown for longer-lasting cognitive and neuroprotective effects.7 benefitsdosingNoopeptEmerging
A Russian-developed dipeptide nootropic roughly a thousand times more potent than piracetam, studied for memory, neuroprotection, and mild anxiolysis.6 benefits4 studiesdosingP21Preclinical
A synthetic CNTF-derived neurotrophic peptide studied in rodents for driving hippocampal neurogenesis, BDNF expression, and memory while sparing the cachexia caused by full-length CNTF.6 benefits4 studiesdosingPE-22-28Preclinical
A synthetic humanin-derived peptide investigated in rodent models for antidepressant-like effects via glial glutamate transporter (GLT-1/EAAT2) upregulation.5 benefitsdosingPinealonPreclinical
A Khavinson-class synthetic tripeptide (Glu-Asp-Arg) targeted at the pineal gland and brain, studied preclinically for neuroprotection, antioxidant defense, and circadian support.6 benefits2 studiesdosingSelankEmerging
A Russian-approved tuftsin-derived heptapeptide that delivers anxiolysis without the sedation, tolerance, or dependence of benzodiazepines.6 benefits5 studiesdosingSemaxEmerging
A Russian-developed ACTH(4-10) heptapeptide that rapidly upregulates BDNF for focus, neuroprotection, and stroke recovery without stimulating cortisol.6 benefits6 studiesdosingVIPEmerging
A 28-amino-acid neuropeptide that binds VPAC1/VPAC2 receptors to drive potent anti-inflammatory, vasodilatory, and circadian-regulating effects across the nervous, immune, and vascular systems.6 benefits2 studiesdosing24 peptides
Longevity & Bioregulators
Khavinson bioregulator peptides and senotherapeutics studied for cellular aging and organ-specific regulation.
BronchogenPreclinical
A short synthetic Khavinson bioregulator peptide positioned to support bronchial epithelium and mucociliary function in age-related and chronic respiratory decline.4 benefits4 studiesdosingCAGPreclinical
A short collagen-derived research peptide studied for cartilage and connective-tissue modulation.3 benefitsdosingCardiogenPreclinical
A synthetic Khavinson tetrapeptide (Ala-Glu-Asp-Arg) researched as a cardiac-tissue-targeted bioregulator for myocardial function and cardiovascular aging.5 benefits4 studiesdosingCarnosineEmerging
A naturally occurring muscle dipeptide that buffers exercise acidosis while scavenging oxidative and glycation byproducts.5 benefits10 studiesCartalaxPreclinical
A Khavinson-family short synthetic peptide positioned as a cartilage bioregulator studied for chondrocyte function and joint tissue support.5 benefits4 studiesdosingChonlutenPreclinical
A Khavinson-class short peptide bioregulator proposed to support bronchial and lung epithelial tissue through tissue-selective gene expression regulation.5 benefits2 studiesdosingCortagenPreclinical
A Khavinson-class tetrapeptide bioregulator studied for gene-regulatory effects in neural and cardiac tissue during aging.6 benefits2 studiesdosingCrystagenPreclinical
A synthetic Khavinson tripeptide (Glu-Asp-Pro) researched as a thymic-tissue bioregulator for T-cell function and immune regulation.3 benefitsEndolutenPreclinical
A Khavinson-class pineal tissue bioregulator proposed to restore age-related circadian rhythm and melatonin synthesis through epigenetic gene regulation.5 benefits1 studiesEpithalonEmerging
A synthetic Khavinson tetrapeptide researched as a telomerase activator and pineal-gland bioregulator for anti-aging and melatonin/circadian normalization.6 benefits3 studiesdosingFOXO4-DRIPreclinical
A first-generation senolytic peptide engineered to selectively destroy senescent "zombie" cells by disrupting the FOXO4-p53 interaction that keeps them alive.6 benefits3 studiesdosingKlothoEmerging
An endogenous anti-aging protein and FGF23 co-receptor whose circulating levels track healthy aging, cognition, and cardiovascular longevity.6 benefits10 studiesLivagenPreclinical
A synthetic Khavinson-class tetrapeptide proposed to act as a liver-specific bioregulator, restoring age- and stress-related changes in hepatocyte function through chromatin-level gene modulation.4 benefits2 studiesdosingOvagenPreclinical
A short synthetic Khavinson-class peptide bioregulator variously positioned for ovarian/reproductive and hepatic tissue support through epigenetic gene-expression modulation.4 benefits1 studiesdosingPancragenPreclinical
A synthetic Khavinson tetrapeptide (Lys-Glu-Asp-Trp) researched for pancreatic-tissue-targeted bioregulation and glucose homeostasis.4 benefitsProstamaxPreclinical
A Khavinson short-peptide 'prostate bioregulator' (Lys-Glu-Asp-Pro) positioned to support prostate tissue in benign prostatic hyperplasia and chronic prostatitis.5 benefits5 studiesdosingRetinalaminEmerging
A bovine-retina-derived Khavinson polypeptide bioregulator studied for neuroprotective and anti-aging effects on photoreceptors and retinal ganglion cells.4 benefits2 studiesdosingSigumirEmerging
A Khavinson-class ultrashort tetrapeptide bioregulator investigated for joint, cartilage, and connective tissue support.4 benefits2 studiesdosingSpleninEmerging
A Khavinson-class ultrashort spleen peptide bioregulator investigated for immune restoration and normalization of blood cell production.3 benefits2 studiesTestagenPreclinical
A short Khavinson-class peptide bioregulator derived from testicular tissue, researched for age-related decline in testosterone production and male reproductive function.5 benefits2 studiesdosingTestolutenPreclinical
A testicular tissue-derived Khavinson peptide bioregulator proposed to restore gene expression in aging Leydig and Sertoli cells to support male reproductive function.5 benefits1 studiesVesugenPreclinical
A Khavinson-class Lys-Glu-Asp tripeptide bioregulator marketed for vascular endothelial health and cardiovascular anti-aging.5 benefits2 studiesdosingVilonPreclinical
The simplest Khavinson bioregulator, a synthetic Lys-Glu dipeptide studied for immune modulation and healthy aging.5 benefits2 studiesdosingVladonixEmerging
A Khavinson-class thymus peptide bioregulator proposed to restore aging immune function by reactivating gene expression in thymic cells and T-lymphocytes.5 benefits2 studies11 peptides
Skin, Hair & Cosmetic
Peptides studied for collagen synthesis, skin remodeling, wrinkle reduction, and hair growth.
AHK-CuPreclinical
A synthetic copper-chelating tripeptide (Ala-His-Lys) positioned as the hair-follicle-focused cousin of GHK-Cu, researched for follicle stimulation and scalp vascularity.6 benefitsdosingArgirelineEmerging
A topical synthetic hexapeptide that softens dynamic expression lines by partially inhibiting the SNARE complex in facial muscles.5 benefits3 studiesdosingCollagen PeptidesModerate
Orally-ingested hydrolyzed collagen peptides that supply connective-tissue building blocks and bioactive dipeptides, with the strongest evidence for skin elasticity, joint comfort, and tendon collagen synthesis.6 benefits6 studiesdosingGHK-CuModerate
A naturally occurring copper-binding tripeptide with the strongest cosmetic-skin evidence record of any peptide, driving collagen synthesis, wound healing, and broad gene-expression effects.7 benefits9 studiesdosingLeuphasylPreclinical
A synthetic enkephalin-mimic pentapeptide marketed as a topical anti-wrinkle cosmetic active that theoretically relaxes facial expression lines.4 benefits1 studiesdosingMatrixylEmerging
A palmitoylated collagen-fragment pentapeptide used topically to mimic matrikine signaling and stimulate dermal collagen synthesis for anti-aging.4 benefits1 studiesdosingPalmitoyl Tripeptide-1Moderate
A palmitoylated form of the copper-binding GHK tripeptide engineered for deep dermal penetration to stimulate collagen and matrix synthesis in anti-aging skincare.5 benefits2 studiesdosingPTD-DBMPreclinical
A cell-penetrating peptide designed to reactivate Wnt/beta-catenin signaling in hair follicles by disrupting the CXXC5-Dishevelled interaction, studied for hair regrowth.4 benefitsRiginPreclinical
A palmitoylated tetrapeptide cosmetic active that suppresses IL-6-driven skin inflammation to protect the collagen matrix from age-related breakdown.4 benefitsdosingSNAP-8Emerging
A topical anti-wrinkle octapeptide marketed as a needle-free, reversible 'topical Botox' that mimics the SNARE-inhibition mechanism of botulinum toxin.5 benefitsdosingSYN-AKEPreclinical
A synthetic snake-venom-mimetic tripeptide marketed as a topical, reversible "botulinum-like" wrinkle relaxer.4 benefits4 peptides
Sexual Health & Melanocortin
Melanocortin and reproductive-axis peptides studied for libido, arousal, and tanning.
Alpha-MSHPreclinical
The prototype endogenous melanocortin peptide that governs pigmentation, inflammation, appetite, and thermoregulation through the MC1R–MC5R receptor family.5 benefits10 studiesMelanotan IFDA-Approved
A linear, MC1R-selective alpha-MSH analog (afamelanotide) that drives UV-independent skin tanning and is FDA-approved as Scenesse for the rare photosensitivity disorder EPP.5 benefits5 studiesdosingMelanotan IIEmerging
A synthetic, non-selective melanocortin receptor agonist best known for UV-independent skin tanning, with bundled effects on sexual arousal and appetite.4 benefits3 studiesdosingPT-141 (Bremelanotide)FDA-Approved
The first FDA-approved centrally acting peptide for a sexual dysfunction indication, working on brain melanocortin receptors rather than peripheral blood flow.5 benefits4 studiesdosing16 peptides
Hormone & Reproductive
Peptides studied for the HPG axis, fertility, and endocrine signaling.
B7-33Preclinical
A single-chain 26-amino-acid relaxin analog engineered as a biased RXFP1 agonist to deliver the anti-fibrotic and cardioprotective effects of H2 relaxin in a simpler synthetic form.6 benefits2 studiesdosingCetrorelixFDA-Approved
An FDA-approved synthetic GnRH antagonist that rapidly suppresses LH and FSH to prevent premature ovulation during IVF cycles.5 benefits5 studiesdosingDesmopressinFDA-Approved
An FDA-approved synthetic vasopressin analogue that raises water reabsorption and clotting factor release while sparing blood-pressure effects.4 benefits8 studiesdosingEPO (Erythropoietin)FDA-Approved
A kidney-derived glycoprotein hormone that drives red blood cell production and is FDA-approved for treating anemia.4 benefitsFSHFDA-Approved
The pituitary glycoprotein hormone that drives gametogenesis in both sexes and forms the backbone of assisted-reproduction ovarian stimulation.4 benefits10 studiesGonadorelinEstablished
Synthetic gonadotropin-releasing hormone that sits at the very top of the reproductive axis, driving pulsatile pituitary LH and FSH release.7 benefits3 studiesdosinghCGEstablished
A long-acting LH mimetic that directly stimulates the testes to make testosterone and preserve fertility, and triggers ovulation in fertility medicine.6 benefits8 studiesdosingKisspeptin-10Emerging
The master upstream trigger of the reproductive axis — a hypothalamic neuropeptide that ignites GnRH release and the entire LH/FSH/testosterone cascade.6 benefits9 studiesdosingLeuprolideFDA-Approved
A synthetic GnRH superagonist that paradoxically shuts down sex-hormone production by desensitizing the pituitary, producing medical castration levels of testosterone and estrogen.5 benefits9 studiesdosingLHModerate
The pituitary gonadotropin that drives testosterone synthesis in men and triggers ovulation in women.5 benefits9 studiesdosingOxytocinFDA-Approved
The endogenous 'love hormone' — a nine-amino-acid neuropeptide, FDA-approved as Pitocin for labor since 1962 and widely researched off-label for social bonding, anxiety, and sexual connection.6 benefits9 studiesdosingRelaxinEmerging
An insulin-family peptide hormone that acts through the RXFP1 receptor to drive vasodilation, boost renal perfusion, and suppress fibrotic tissue remodeling.5 benefits8 studiesdosingTeriparatideFDA-Approved
A synthetic parathyroid hormone fragment and the first FDA-approved anabolic agent that builds new bone rather than merely slowing its loss.5 benefits6 studiesdosingTRHEmerging
A hypothalamic tripeptide that drives TSH release from the pituitary while acting as a broad CNS neuromodulator with arousal-promoting and neuroprotective effects.5 benefits2 studiesdosingTriptorelinFDA-Approved
A long-acting synthetic GnRH agonist that is FDA-approved for hormonal suppression, but whose brief initial LH/FSH flare drives its off-label reputation as a single-shot HPG-axis restart.5 benefits6 studiesdosingVasopressinFDA-Approved
An endogenous hypothalamic nonapeptide hormone that regulates water balance, blood pressure, and stress-related memory, and is FDA-approved as a vasopressor for shock.5 benefits7 studiesdosing13 peptides
Immune & Mitochondrial
Peptides studied for immune modulation, mitochondrial function, and cellular energy.
CGRPEstablished
A 37-amino-acid sensory neuropeptide that is one of the body's most potent vasodilators and the validated pharmacological target behind modern anti-migraine therapy.4 benefits10 studiesGlutathioneModerate
The body's master endogenous antioxidant tripeptide — foundational redox biology whose supplemental benefits depend heavily on route and formulation.8 benefits8 studiesdosingHumaninPreclinical
The first mitochondrial-derived peptide ever described — a cytoprotective, anti-apoptotic signaling molecule encoded inside mitochondrial DNA.6 benefits12 studiesdosingLeu-EnkephalinPreclinical
An endogenous opioid pentapeptide that binds delta and mu opioid receptors to modulate pain signaling and immune activity.3 benefits1 studiesMet-EnkephalinEmerging
An endogenous opioid pentapeptide that doubles as the opioid growth factor, acting as a tonic brake on cell proliferation and immune activity.5 benefits4 studiesMOTS-cPreclinical
A 16-amino-acid mitochondrial-derived peptide that activates AMPK to mimic the metabolic effects of exercise and improve insulin sensitivity.6 benefits10 studiesdosingNAD+Emerging
The central cellular energy coenzyme whose age-related decline made it the most commercially successful longevity compound of the last decade — though most of the rigorous evidence sits with its oral precursors.6 benefits8 studiesdosingPNC-27Preclinical
A p53-derived research peptide that selectively ruptures the membranes of cancer cells by targeting surface-expressed HDM-2, while sparing normal cells.5 benefits1 studiesSS-31 (Elamipretide)Moderate
A first-in-class cardiolipin-targeting tetrapeptide that concentrates in the inner mitochondrial membrane to stabilize cristae, protect the electron transport chain, and reduce reactive oxygen species at the source.6 benefits9 studiesdosingThymalinEmerging
A thymus-derived peptide complex used in Russian medicine to restore age-related immune decline and reduce all-cause mortality in the elderly.6 benefits2 studiesdosingThymogenEmerging
A synthetic Glu-Trp dipeptide bioregulator that targets thymus-dependent cellular immunity and T-cell function.6 benefits2 studiesdosingThymosin Alpha-1Established
A thymus-derived immune-modulating peptide, approved abroad as Zadaxin for hepatitis, that reshapes rather than simply boosts immune response.7 benefits2 studiesdosingThymulinEmerging
A zinc-dependent thymic nonapeptide that drives T-lymphocyte differentiation and helps rebalance the aging, inflammation-prone immune system.4 benefits2 studiesdosing
