Peptide Directory
Category · 13 peptides
Immune & Mitochondrial
Peptides studied for immune modulation, mitochondrial function, and cellular energy.
CGRPEstablished
A 37-amino-acid sensory neuropeptide that is one of the body's most potent vasodilators and the validated pharmacological target behind modern anti-migraine therapy.- Potent vasodilation
- Pain and nociceptive modulation
- Bone repair and osseointegration
GlutathioneModerate
The body's master endogenous antioxidant tripeptide — foundational redox biology whose supplemental benefits depend heavily on route and formulation.- Master intracellular antioxidant
- Phase II liver detoxification
- Liver support in fatty liver disease
HumaninPreclinical
The first mitochondrial-derived peptide ever described — a cytoprotective, anti-apoptotic signaling molecule encoded inside mitochondrial DNA.- Neuroprotection
- Anti-apoptotic / cytoprotection
- Metabolic improvement
Leu-EnkephalinPreclinical
An endogenous opioid pentapeptide that binds delta and mu opioid receptors to modulate pain signaling and immune activity.- Pain modulation
- Anti-inflammatory activity
- Immune modulation
Met-EnkephalinEmerging
An endogenous opioid pentapeptide that doubles as the opioid growth factor, acting as a tonic brake on cell proliferation and immune activity.- Immune modulation
- Cell proliferation regulation
- Anti-inflammatory activity
MOTS-cPreclinical
A 16-amino-acid mitochondrial-derived peptide that activates AMPK to mimic the metabolic effects of exercise and improve insulin sensitivity.- Improved insulin sensitivity
- Exercise mimicry
- Metabolic homeostasis and fat oxidation
NAD+Emerging
The central cellular energy coenzyme whose age-related decline made it the most commercially successful longevity compound of the last decade — though most of the rigorous evidence sits with its oral precursors.- Restores age-associated NAD+ decline
- Supports mitochondrial energy production
- Activates sirtuin longevity pathways
PNC-27Preclinical
A p53-derived research peptide that selectively ruptures the membranes of cancer cells by targeting surface-expressed HDM-2, while sparing normal cells.- Selective cancer cell membranolysis
- Activity across multiple cancer types
- Non-apoptotic killing mechanism
SS-31 (Elamipretide)Moderate
A first-in-class cardiolipin-targeting tetrapeptide that concentrates in the inner mitochondrial membrane to stabilize cristae, protect the electron transport chain, and reduce reactive oxygen species at the source.- Mitochondrial membrane stabilization
- Reduced ROS at the source
- Preserved ATP production and cardioprotection
ThymalinEmerging
A thymus-derived peptide complex used in Russian medicine to restore age-related immune decline and reduce all-cause mortality in the elderly.- Immune restoration in aging
- Reduced all-cause mortality (elderly cohorts)
- Cytokine and inflammatory modulation
ThymogenEmerging
A synthetic Glu-Trp dipeptide bioregulator that targets thymus-dependent cellular immunity and T-cell function.- Immune system modulation
- Thymic function support
- Enhanced T-cell immunity
Thymosin Alpha-1Established
A thymus-derived immune-modulating peptide, approved abroad as Zadaxin for hepatitis, that reshapes rather than simply boosts immune response.- Hepatitis B adjunct therapy
- Immune modulation, not blunt stimulation
- T-cell and NK-cell enhancement
ThymulinEmerging
A zinc-dependent thymic nonapeptide that drives T-lymphocyte differentiation and helps rebalance the aging, inflammation-prone immune system.- Immune modulation
- T-cell maturation
- NK cell support

