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Peptide Directory

Category · 4 peptides

Sexual Health & Melanocortin

Melanocortin and reproductive-axis peptides studied for libido, arousal, and tanning.

Alpha-MSHPreclinical
The prototype endogenous melanocortin peptide that governs pigmentation, inflammation, appetite, and thermoregulation through the MC1R–MC5R receptor family.
  • Anti-inflammatory signaling
  • Immunomodulation and tolerance
  • Appetite and energy homeostasis
10 studies
Melanotan IFDA-Approved
A linear, MC1R-selective alpha-MSH analog (afamelanotide) that drives UV-independent skin tanning and is FDA-approved as Scenesse for the rare photosensitivity disorder EPP.
  • Photoprotection in EPP (approved indication)
  • UV-independent skin tanning
  • High MC1R selectivity vs Melanotan II
5 studiesdosing
Melanotan IIEmerging
A synthetic, non-selective melanocortin receptor agonist best known for UV-independent skin tanning, with bundled effects on sexual arousal and appetite.
  • UV-independent skin tanning
  • Central sexual arousal and erectile function
  • Appetite suppression
3 studiesdosing1 stacks
PT-141 (Bremelanotide)FDA-Approved
The first FDA-approved centrally acting peptide for a sexual dysfunction indication, working on brain melanocortin receptors rather than peripheral blood flow.
  • Central sexual arousal and desire
  • FDA-approved treatment for HSDD in women
  • Off-label male erectile dysfunction
4 studiesdosing4 stacks
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